Navigating reflux disease after achalasia treatments: Balancing risks and benefits

• Published in: World journal of gastroenterology : WJG Vol. 30; no. 21; pp. 2740 - 2743
• Main Authors: Griffiths, Ewen A, Wong, Enoch
• Format: Journal Article
• Language: English
• Published: United States Baishideng Publishing Group Inc 07.06.2024
• Subjects: Deglutition Disorders - diagnosis; Deglutition Disorders - etiology; Deglutition Disorders - therapy; Esophageal Achalasia - diagnosis; Esophageal Achalasia - physiopathology; Esophageal Achalasia - surgery; Esophageal Achalasia - therapy; Fundoplication - adverse effects; Fundoplication - methods; Gastroesophageal Reflux - diagnosis; Gastroesophageal Reflux - etiology; Gastroesophageal Reflux - therapy; Heller Myotomy - adverse effects; Heller Myotomy - methods; Humans; Laparoscopy - adverse effects; Laparoscopy - methods; Natural Orifice Endoscopic Surgery - adverse effects; Natural Orifice Endoscopic Surgery - methods; Postoperative Complications - epidemiology; Postoperative Complications - etiology; Postoperative Complications - prevention & control; Risk Assessment; Risk Factors; Treatment Outcome; Fundoplication; Achalasia; Laparoscopic heller’s myotomy; Gastro-esophageal reflux disease; Peroral endoscopic myotomy
• ISSN: 2219-2840; 1007-9327; 2219-2840
• DOI: 10.3748/wjg.v30.i21.2740

The peroral endoscopic myotomy (POEM) procedure has revolutionized the management of achalasia in many centres around the world as it offers patients a minimally invasive endoscopic solution to their dysphagia caused by achalasia. Alongside its success in alleviating dysphagia, concerns regarding postoperative gastroesophageal reflux disease have emerged as a pertinent issue which are not fully resolved. In this study, Nabi have comprehensively reviewed the topic of the prediction, prevention and management of gastroesophageal reflux after POEM. POEM is a purely endoscopic procedure which is usually performed without any anti-reflux procedure. Certain patients may be better served by a laparoscopic Heller's myotomy and fundoplication and it is important that gastroenterologists and surgeons provide comprehensive risks and benefits of each achalasia treatment option so that patients can decide what treatment is best for them. This article by Nabi provides a comprehensive review of the current status of this issue to allow these discussions to occur.