Interesting coincidence of atypical TSH-secreting pituitary adenoma and chronic lymphocytic leukemia

Thyrotropin-secreting adenomas (TSH-oma) are very rare pituitary tumours. They are macroadenomas usually presenting with signs and symptoms of hyperthyroidism, and mass effects. They can co-secrete other hormones such as growth hormone or prolactin. Different malignancies, including haematological o...

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Bibliographic Details
Published inEndokrynologia Polska Vol. 65; no. 2; pp. 144 - 147
Main Authors Bolanowski, Marek, Zieliński, Grzegorz, Jawiarczyk-Przybyłowska, Aleksandra, Maksymowicz, Maria, Potoczek, Stanisław, Syrycka, Joanna, Podgórski, Jan K
Format Journal Article
LanguageEnglish
Published Poland Wydawnictwo Via Medica 2014
Subjects
Adenoma - complications
Adenoma - diagnosis
Adenoma - secretion
Adenoma - surgery
Agent Orange
Diagnosis, Differential
Humans
Hyperthyroidism - complications
Leukemia
Leukemia, Lymphocytic, Chronic, B-Cell - complications
Leukemia, Lymphocytic, Chronic, B-Cell - diagnosis
Male
Middle Aged
Pituitary Neoplasms - complications
Pituitary Neoplasms - diagnosis
Pituitary Neoplasms - secretion
Pituitary Neoplasms - surgery
Thyrotropin - secretion
Tumors
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Summary:Thyrotropin-secreting adenomas (TSH-oma) are very rare pituitary tumours. They are macroadenomas usually presenting with signs and symptoms of hyperthyroidism, and mass effects. They can co-secrete other hormones such as growth hormone or prolactin. Different malignancies, including haematological ones, are reported in patients with pituitary diseases. Chronic lymphocytic leukemia (CLL) occurs mostly in older patients, more often in males. CLL is associated with increased risk of second malignancies such as other blood neoplasms, skin and solid tumours. We present a successful neurosurgical outcome in a patient with an interesting coincidence of atypical TSH-oma and asymptomatic CLL.
ISSN:0423-104X
2299-8306
DOI:10.5603/EP.2014.0020