The puzzle of somatostatin: action, receptors, analogues and therapy

The scientific search for the revelation of the multiple physiological aspects of somatostatin has already begun. Investigators have managed to clarify many pathophysiological processes that have been influenced or regulated by somatostatin. The focus of future research seems to be the therapeutic a...

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Bibliographic Details
Published inHepato-gastroenterology Vol. 52; no. 66; p. 1771
Main Authors Panteris, V, Karamanolis, D G
Format Journal Article
LanguageEnglish
Published Greece 01.11.2005
Subjects
Autoimmunity - drug effects
Female
Gastrointestinal Neoplasms - drug therapy
Gastrointestinal Neoplasms - immunology
Gastrointestinal Neoplasms - physiopathology
Humans
Inflammatory Bowel Diseases - drug therapy
Inflammatory Bowel Diseases - immunology
Inflammatory Bowel Diseases - physiopathology
Intestinal Mucosa - drug effects
Male
Receptors, Somatostatin - physiology
Sensitivity and Specificity
Somatostatin - analogs & derivatives
Somatostatin - metabolism
Somatostatin - therapeutic use
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Summary:The scientific search for the revelation of the multiple physiological aspects of somatostatin has already begun. Investigators have managed to clarify many pathophysiological processes that have been influenced or regulated by somatostatin. The focus of future research seems to be the therapeutic application of this accumulated knowledge. The aim of this study is to collect the available information on the action, receptors and use of somatostatin analogues in human tissues. For this reason findings were based on Internet search and complete studies with abstracts written in English. A special mention on the influence of somatostatin on the immune system and inflammatory bowel disease is also included.
ISSN:0172-6390