Severe angioedema caused by banana allergy under tacrolimus immunosuppression

• Published in: Transplantation proceedings Vol. 37; no. 10; pp. 4251 - 4253
• Main Authors: YILMAZ, A, ARTAN, R, UGUZ, A, ARSLAN, G, AKCAM, M
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Science 01.12.2005
• Subjects: Allergic diseases; Biliary Atresia - surgery; Biological and medical sciences; Cyclosporine - therapeutic use; Female; Food Hypersensitivity; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Humans; Immunoglobulin E - blood; Immunopathology; Immunosuppressive Agents - therapeutic use; Infant; Liver Transplantation - immunology; Medical sciences; Musa; Skin allergic diseases. Stinging insect allergies; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Tacrolimus - therapeutic use; Tissue, organ and graft immunology; Tomography, X-Ray Computed; Trachea - diagnostic imaging; Treatment Outcome; Immunopathology; Allergy; Monocotyledones; Skin disease; Calcineurin inhibitor; Lactone; Musaceae; Transplantation; Macrolide; Banana; Immunomodulator; Medicine; Immunosuppression; Musa; Angioneurotic edema; Treatment; Tacrolimus; Surgery; Angiospermae; Graft; Spermatophyta; Immunosuppressive agent; Antibacterial agent; Severe
• ISSN: 0041-1345; 1873-2623
• DOI: 10.1016/j.transproceed.2005.10.006

Occurrences of allergic reactions induced by various foods have been reported in pediatric liver graft recipients receiving tacrolimus immunosuppression. We describe herein a female infant, who was admitted to our hospital with life-threatening angioedema because of banana hypersensitivity, 8 months after orthotopic liver transplantation. Food allergies should be screened in all tacrolimus-immunosuppressed pediatric liver recipients who show suggestive clinical symptoms. Banana must be added to allergen batteries during etiologic investigations. Cyclosporine represents an option for drug conversion to prevent organ rejection.