Two Japanese cases with MAGIC syndrome (Mouth and Genital Ulcers with Inflamed Cartilage)

• Published in: Clinical and experimental rheumatology Vol. 24; no. 5; pp. S113 - S114
• Main Authors: NANKE, Y, KAMATANI, N, KOBASHIGAWA, T, YAGO, T, FURUYA, T, KOTAKE, S
• Format: Journal Article
• Language: English
• Published: Pisa Clinical and Experimental Rheumatology 01.09.2006
• Subjects: Adult; Behcet Syndrome - complications; Behcet Syndrome - pathology; Biological and medical sciences; Cartilage - pathology; Diseases of the osteoarticular system; Female; Genital Diseases, Female; Genital Diseases, Male; Humans; Inflammatory joint diseases; Male; Medical sciences; Middle Aged; Miscellaneous. Osteoarticular involvement in other diseases; Oral Ulcer; Polychondritis, Relapsing - complications; Polychondritis, Relapsing - pathology; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; Syndrome; Skin disease; MAGIC syndrome; Diseases of the osteoarticular system; Relapsing polychondritis; Cardiovascular disease; Genital diseases; Vascular disease; Cartilage; Vasculitis; Nose; Systemic disease; ENT disease; Ulcer; Hypouricemic agent; Stomatology; Rheumatology; Behçet syndrome; Oral cavity; Eye disease; Chronic; Behçet's disease; Chondropathy; Treatment; Ear; Colchicine
• ISSN: 0392-856X; 1593-098X

We describe two cases, a 28-year-old woman and a 46-year-old man, with mouth and genital ulcers with inflamed cartilage (chondritis of the nose and ears) (MAGIC syndrome). The conditions of both patients were resolved by treatment with corticosteroid and colchicine. We also review the English literature related to this rare syndrome.