Sarcoidosis mimicking ischaemic ventricular arrhythmia and pulmonary embolism

Sarcoidosis is a multisystem granulomatous disorder characterised pathologically by the presence of noncaseating granulomas in the organs involved. Cardiac involvement, although well known, is rare. We describe a 72-year-old patient who was admitted to the intensive care unit after coronary artery b...

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Published inNetherlands journal of medicine Vol. 63; no. 2; pp. 70 - 73
Main Authors DE JAGER, C. P. C, JESSURUN, E. R, JANSEN, E. K, VERHEIJ, J, GIRBES, A. R. J, VAN SCHIJNDEL, R. J. M. Strack
Format Journal Article
LanguageEnglish
Published Alphen aan den Rijn Van zuiden 01.02.2005
Subjects
Aged
Biological and medical sciences
Biopsy, Needle
Coronary Angiography
Coronary Artery Bypass - methods
Diagnosis, Differential
Disease Progression
Emergency Service, Hospital
Fatal Outcome
Female
General aspects
Heart Diseases - diagnosis
Heart Diseases - pathology
Humans
Immunohistochemistry
Medical sciences
Myocardial Ischemia - diagnosis
Myocardial Ischemia - pathology
Pulmonary Embolism - diagnosis
Pulmonary Embolism - therapy
Sarcoidosis - diagnosis
Sarcoidosis - pathology
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
Tachycardia, Ventricular - diagnosis
Tachycardia, Ventricular - drug therapy
Vascular disease
Pulmonary embolism
Medicine
Ischemia
Sarcoidosis
Arrhythmia
Respiratory disease
Heart disease
Systemic disease
Cardiovascular disease
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Summary:Sarcoidosis is a multisystem granulomatous disorder characterised pathologically by the presence of noncaseating granulomas in the organs involved. Cardiac involvement, although well known, is rare. We describe a 72-year-old patient who was admitted to the intensive care unit after coronary artery bypass grafting. She developed refractory right and left ventricular failure complicated by multiple organ failure and died three days later. Postmortem examination revealed extensive sarcoidosis. On hindsight, preoperative ventricular tachycardia and an abnormal perfusion-ventilation scintigraphy of the lungs were manifestations of an underlying sarcoidosis.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ISSN:0300-2977
1872-9061