Ischemic Stroke Management: Posthospitalization and Transition of Care

• Published in: American family physician Vol. 108; no. 1; pp. 70 - 77
• Main Authors: Larson, Scott T, Ray, Brigit E, Wilbur, Jason
• Format: Journal Article
• Language: English
• Published: United States American Academy of Family Physicians 01.07.2023
• Subjects: Anticoagulants - therapeutic use; Aspirin; Atrial Fibrillation - complications; Atrial Fibrillation - diagnosis; Atrial Fibrillation - therapy; Blood pressure; Blood tests; Cardiac arrhythmia; Cardiovascular disease; Clinical trials; Diabetes; Diabetes Mellitus, Type 2 - drug therapy; Diet; Disease prevention; Drug use; Exercise; Genetic disorders; Heart attacks; Humans; Hypertension; Ischemic Attack, Transient - diagnosis; Ischemic Attack, Transient - therapy; Ischemic Stroke - drug therapy; Laboratories; Lifestyles; Lipids; Medical imaging; Metabolic disorders; Mutation; Patient Transfer; Patients; Physical fitness; Platelet Aggregation Inhibitors - therapeutic use; Risk factors; Stroke; Stroke - etiology; Stroke - prevention & control; Transient ischemic attack; United States > US
• ISSN: 0002-838X; 1532-0650

Ischemic stroke is a major cause of morbidity and mortality worldwide. Ischemic stroke and transient ischemic attack exist on a continuum of the same disease process. Ischemic stroke is common, and more than 85% of stroke risk is attributed to modifiable risk factors. The initial management of acute stroke is usually performed in the emergency department and hospital settings. Family physicians have a key role in follow-up, ensuring that a complete diagnostic evaluation has been performed, addressing modifiable risk factors, facilitating rehabilitation, and managing chronic sequelae. Secondary prevention of ischemic stroke includes optimization of chronic disease management (e.g., hypertension, type 2 diabetes mellitus, dyslipidemia), nonpharmacologic lifestyle interventions (e.g., diet changes, exercise, substance use counseling), and pharmacologic interventions. Dual antiplatelet therapy with aspirin and clopidogrel is generally indicated for minor noncardioembolic ischemic strokes and high-risk transient ischemic attacks and should be converted to single antiplatelet therapy after 21 to 90 days. Secondary prevention of cardioembolic stroke requires long-term anticoagulation. Direct oral anticoagulants are preferred over warfarin for patients with nonvalvular atrial fibrillation. Poststroke problems with mobility, balance, cognition, dysphagia, and depression are common. Rehabilitation involves a multidisciplinary, multimodal approach that includes physical therapy, speech therapy, and treatment of chronic pain and poststroke depression.