Addison's disease due to Histoplasma duboisii infection of the adrenal glands

Histoplasmosis is a fungal infection caused by Histoplasma capsulatum. In the normal individual, both disseminated histoplasmosis and symptomatic adrenal histoplasmosis are rare. Herein, we describe the case of a 50-year-old gentleman residing in western Sudan who presented with a 7-month history of...

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Bibliographic Details
Published inSaudi medical journal Vol. 29; no. 6; p. 904
Main Authors Mudawi, Hatim M, Elamin, Elwaleed M, Baraka, Omer Z, El-Hassan, Ahmed M
Format Journal Article
LanguageEnglish
Published Saudi Arabia 01.06.2008
Subjects
Addison Disease - etiology
Adrenal Gland Diseases - complications
Histoplasma
Histoplasmosis - complications
Humans
Male
Middle Aged
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Summary:Histoplasmosis is a fungal infection caused by Histoplasma capsulatum. In the normal individual, both disseminated histoplasmosis and symptomatic adrenal histoplasmosis are rare. Herein, we describe the case of a 50-year-old gentleman residing in western Sudan who presented with a 7-month history of generalized body weakness, easy fatigue, and frequent attacks of vomiting and diarrhea. Physical examination and laboratory investigations confirmed the diagnosis of Addison's disease due to Histoplasma capsulatum var duboisii infection of the adrenal glands. He was treated with intravenous hydrocortisone, followed by oral prednisolone and itraconazole.
ISSN:0379-5284