Schizencephaly: report of eleven cases

A retrospective study comparing clinical and computerized tomography (CT) in 11 patients diagnosed as having schizencephaly was conducted. Seven of these patients were girls and four boys. Six of them had tetraparesis, three hemiparesis and one no motor deficits. Six had epilepsy and ten development...

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Published inArquivos de neuro-psiquiatria Vol. 59; no. 2-A; pp. 244 - 249
Main Authors Amaral, J G, Yanaga, R H, Geissler, H J, de Carvalho Neto, A, Bruck, I, Antoniuk, S A
Format Journal Article
LanguageEnglish
Portuguese
Published Brazil 01.06.2001
Subjects
Adolescent
Brain - abnormalities
Brain - diagnostic imaging
Child
Child, Preschool
Female
Humans
Infant
Male
Retrospective Studies
Tomography, X-Ray Computed
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Summary:A retrospective study comparing clinical and computerized tomography (CT) in 11 patients diagnosed as having schizencephaly was conducted. Seven of these patients were girls and four boys. Six of them had tetraparesis, three hemiparesis and one no motor deficits. Six had epilepsy and ten developmental delay. On CT examinations, 7 patients were found as having bilateral clefts and four unilateral defect. Eight had opened lip clefts and four had a closed lip defect. The commonest associated anomaly was an absent septum pellucidum (n=9), followed by subependymal nodules (n=4), hydrocephalus (n=2) and microcephaly (n=1). Despite magnetic resonance image is the gold-standard to diagnose neuronal migration anomalies, CT can be useful in showing typical aspects of schizencephaly.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0004-282X
DOI:10.1590/S0004-282X2001000200019