Experimental kerosene poisoning in goats

Eighteen young native male and female goats were divided into 3 equal groups. Kerosene was given to Groups 1, 2 and 3 as single doses of 10, 20 or 40 ml/kg bw respectively. Clinical signs In-Group 1 were mild behavioral changes and in Group 2 were mild to moderate bloat, coughing and behavioral chan...

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Bibliographic Details
Published inVeterinary and human toxicology Vol. 42; no. 6; p. 354
Main Authors Aslani, M R, Movassaghi, A R, Mohri, M, Vojdani, M
Format Journal Article
LanguageEnglish
Published United States 01.12.2000
Subjects
Animals
Brain - pathology
Cough - veterinary
Edema - veterinary
Female
Goat Diseases - chemically induced
Goat Diseases - pathology
Goats
Histocytochemistry - veterinary
Kerosene - poisoning
Kidney - pathology
Liver - pathology
Male
Pleuropneumonia - veterinary
Pneumonia - veterinary
Vomiting - veterinary
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Summary:Eighteen young native male and female goats were divided into 3 equal groups. Kerosene was given to Groups 1, 2 and 3 as single doses of 10, 20 or 40 ml/kg bw respectively. Clinical signs In-Group 1 were mild behavioral changes and in Group 2 were mild to moderate bloat, coughing and behavioral changes. None of the goats of Groups 1 and 2 died. Goats of Group 3 had severe signs of poisoning and died within 4 h to 11 d after dosing with clinical signs of severe bloat, frequent coughing, vomiting, and expelling of kerosene from the mouth and nose. Star-gazing, depression, recumbency and dyspnea also occurred. Postmortem changes in Group 3 were gangrenous pneumonia, pleuropneumonia, congestion in brain and kidney, perivascular and perineuronal edema in brain tissue, and renal nephrosis.
ISSN:0145-6296