Drug discovery and development through the genetic engineering of antibiotic-producing microorganisms

This perspective examines one area - antibiotic discovery and production - where molecular biologists and medicinal chemists are collaborating to drive the quest for new drugs and to improve production of old ones.

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Bibliographic Details
Published inJournal of medicinal chemistry Vol. 32; no. 5; pp. 929 - 936
Main Authors Hutchinson, C R, Borell, C W, Otten, S L, Stutzman-Engwall, K J, Wang, Y G
Format Journal Article
LanguageEnglish
Published United States 01.05.1989
Subjects
Anti-Bacterial Agents - biosynthesis
Drug Design
Genetic Engineering
Streptomyces - genetics
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Summary:This perspective examines one area - antibiotic discovery and production - where molecular biologists and medicinal chemists are collaborating to drive the quest for new drugs and to improve production of old ones.
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ISSN:0022-2623
DOI:10.1021/jm00125a001