The effect of oral aspartame administration on the balance of magnesium in the rat

The aim of the present work was to determine the effect of aspartame administration on the excretion of magnesium and its distribution in the various rat tissues and organs. The present results have shown that aspartame administration influences the balance of magnesium in the organism, since in som...

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Bibliographic Details
Published inMagnesium research Vol. 14; no. 3; p. 189
Main Authors Kovatsi, L, Tsouggas, M
Format Journal Article
LanguageEnglish
Published England 01.09.2001
Subjects
Administration, Oral
Animals
Aspartame - administration & dosage
Aspartame - pharmacology
Chelating Agents - metabolism
Feces - chemistry
Magnesium - metabolism
Magnesium - urine
Male
Rats
Rats, Wistar
Tissue Distribution
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Summary:The aim of the present work was to determine the effect of aspartame administration on the excretion of magnesium and its distribution in the various rat tissues and organs. The present results have shown that aspartame administration influences the balance of magnesium in the organism, since in some organs and tissues (heart, lungs, kidneys, adrenals, jejunum, hair and blood) it is accumulated, while other organs (liver and testes) are deprived of it. Aspartame administration also affects the excretion of magnesium from the organism, since it decreases the concentration of magnesium in both urine and feces.
ISSN:0953-1424