Apparent differences between Asian and Caucasians in alcohol-induced liver changes

For some time the authors have noticed apparent differences between their Asian and Caucasian male patients in the severity of alcohol-induced liver changes. To test the validity of this hypothesis a retrospective study was carried out. Eighty-one consecutive Asian patients admitted over an 18 month...

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Published inBritish journal of addiction Vol. 83; no. 12; pp. 1461 - 1462
Main Authors Wilson, D T, Marjot, D H, Spencer-Peet, J, Fink, R
Format Journal Article
LanguageEnglish
Published England 01.12.1988
Subjects
Asia - ethnology
Cross-Cultural Comparison
England
Humans
Liver Diseases, Alcoholic - ethnology
England
Asia
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Summary:For some time the authors have noticed apparent differences between their Asian and Caucasian male patients in the severity of alcohol-induced liver changes. To test the validity of this hypothesis a retrospective study was carried out. Eighty-one consecutive Asian patients admitted over an 18 month period to the Regional Alcoholism & Drug Dependence Unit were matched by age with 81 Caucasian patients admitted within the same period. There was no significant difference in respect of bilirubin, albumin and alkaline phosphatase between the groups. However, AST and GGT activities in the Asian Group were significantly greater than values found in the Caucasian group. Results suggest that the Asian alcoholic patient seem more liable to suffer from alcohol-induced liver damage than the Caucasian.
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SourceType-Scholarly Journals-1
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ISSN:0952-0481