Epoxidation and fate of ( 14 C)aldrin in insecticide-resistant and susceptible populations of mosquitofish (Gambusia affinis)

1 susceptible and 2 resistant populations of Gambusia affinis were treated with [ super(14)C] aldrin to determine differences in aldrin epoxidation between susceptible and resistant mosquito fish brains and livers. Resistant mosquito fish converted aldrin to dieldrin and/or water-soluble material at...

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Bibliographic Details
Published inJournal of agricultural and food chemistry Vol. 21; no. 3; pp. 428 - 429
Main Authors Wells, M R, Ludke, J L, Yarbrough, J D
Format Journal Article
LanguageEnglish
Published United States 01.05.1973
Subjects
Aldrin - metabolism
Animals
Brain - metabolism
Brain Chemistry
Carbon Isotopes
Drug Resistance
Fishes
Freshwater
Liver - analysis
Liver - metabolism
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Summary:1 susceptible and 2 resistant populations of Gambusia affinis were treated with [ super(14)C] aldrin to determine differences in aldrin epoxidation between susceptible and resistant mosquito fish brains and livers. Resistant mosquito fish converted aldrin to dieldrin and/or water-soluble material at a greater rate than susceptible mosquitofish. These data would tend to support rate of detoxification as a possible mechanism of resistance to aldrin in the mosquitofish.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0021-8561
DOI:10.1021/jf60187a010