Detection with a monoclonal antibody of a polysaccharide antigen, excreted in the urine, in the schistosomiasis intercalatum focus of Edea (Cameroon)

The detection in the urine specimens of a sample of the inhabitants of Edea of a polysaccharide antigen characteristic for the genus Schistosoma, with monoclonal antibody by means of the inhibition of a passive haemagglutination test, shows that this technique is very sensitive for measuring prevale...

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Published inTropical medicine and parasitology Vol. 41; no. 1; p. 40
Main Authors Ripert, C, Vincendeau, P, Macaigne, F, Appriou, M, Biessy, H, Tribouley, J, Tribouley-Duret, J, Garnier, T
Format Journal Article
LanguageEnglish
Published Germany 01.03.1990
Subjects
Adolescent
Adult
Animals
Antibodies, Helminth - immunology
Antibodies, Monoclonal - immunology
Antigens, Helminth - urine
Cameroon - epidemiology
Child
Female
Fluorescent Antibody Technique
Hemagglutination Tests
Humans
Male
Middle Aged
Polysaccharides - urine
Prevalence
Schistosoma - immunology
Schistosomiasis - diagnosis
Schistosomiasis - epidemiology
Schistosomiasis - urine
Cameroon
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Summary:The detection in the urine specimens of a sample of the inhabitants of Edea of a polysaccharide antigen characteristic for the genus Schistosoma, with monoclonal antibody by means of the inhibition of a passive haemagglutination test, shows that this technique is very sensitive for measuring prevalence of schistosomiasis due to S. intercalatum. In Edea, looking for eggs in stool specimens gives a low prevalence rate of the disease because of the low parasitic load. The prevalence by age, according to the voiding of eggs, is evoluting parallel to the excretion of the antigen.
ISSN:0177-2392