Radiolabeled antibodies : results and potential in cancer therapy

Radiolabeled antibodies are analyzed from the classical approach in radiation oncology being compared to geometric isotopic implants, external radiation, and tumor-dose response and energy of the isotope used for cytotoxicity. In addition, physiological factors that limit antibody uptake, varied rou...

Full description

Saved in:
Bibliographic Details
Published inCancer research (Chicago, Ill.) Vol. 50; no. 3; pp. 1011s - 1013s
Main Authors ORDER, S. E, SLEEPER, A. M, STILLWAGON, G. B, KLEIN, J. L, LEICHNER, P. K
Format Journal Article
LanguageEnglish
Published Philadelphia, PA American Association for Cancer Research 01.02.1990
Subjects
Antibodies, Neoplasm - immunology
Biological and medical sciences
Dose-Response Relationship, Radiation
Humans
Medical sciences
Neoplasms - radiotherapy
Radiation therapy and radiosensitizing agent
Radioisotopes - administration & dosage
Radiotherapy Dosage
Treatment with physical agents
Treatment. General aspects
Tumors
Online AccessGet full text

Cover

More Information
Summary:Radiolabeled antibodies are analyzed from the classical approach in radiation oncology being compared to geometric isotopic implants, external radiation, and tumor-dose response and energy of the isotope used for cytotoxicity. In addition, physiological factors that limit antibody uptake, varied routes of administration, toxicity of treatment, as well as present clinical progress are reviewed.
ISSN:0008-5472
1538-7445