Health impact of peptic ulcer in the United States

• Published in: The American journal of gastroenterology Vol. 92; no. 4; p. 614
• Main Authors: Sonnenberg, A, Everhart, J E
• Format: Journal Article
• Language: English
• Published: United States 01.04.1997
• Subjects: Adolescent; Adult; Age Distribution; Aged; Confidence Intervals; Cost of Illness; Costs and Cost Analysis; Female; Health Status; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Peptic Ulcer - economics; Peptic Ulcer - epidemiology; Prevalence; Random Allocation; Sex Distribution; Sickness Impact Profile; Surveys and Questionnaires; United States - epidemiology; United States
• ISSN: 0002-9270; 1572-0241

To assess the general outcome and impact of current and previous peptic ulcer disease on health status in the United States. During the National Health Interview Survey of 1989, a special questionnaire on digestive diseases was administered to 41,457 randomly selected individuals. Various measures of impaired health in ulcer patients were expressed by their age- and sex-standardized prevalence rates. Ten to 15% of all subjects with a recent ulcer reported that they had been in poor health, incapable of major activity, or unable to work for some time during the 12 months preceding the interview. Twenty to 25% of the subjects with recent ulcers complained about restricted activity and had spent 7 or more days per year in bed. About 40% of all ulcer subjects had seen a physician five or more times within 12 months before the interview. These percentages were significantly lower in patients with previous ulcer histories but no active ulcer within 12 months, but they were still significantly higher than in subjects with no ulcer history at all. In the United States, expenditures attributed to recent ulcers amounted to $5.65 billion per year. In the United States, peptic ulcer disease is associated with major morbidity. Ulcer cure would result in large economic and medical savings.