Epidermoid cancer of the anal margin: pathologic features, treatment, and clinical results

• Published in: The American journal of surgery Vol. 149; no. 1; pp. 95 - 101
• Main Authors: GREENALL, M. J, QUAN, S. H. Q, STEARNS, M. W, URMACHER, C, DECOSSE, J. J
• Format: Conference Proceeding Journal Article
• Language: English
• Published: New York, NY Elsevier 1985
• Subjects: Adult; Aged; Anus Neoplasms - classification; Anus Neoplasms - mortality; Anus Neoplasms - pathology; Anus Neoplasms - surgery; Biological and medical sciences; Carcinoma, Squamous Cell - classification; Carcinoma, Squamous Cell - mortality; Carcinoma, Squamous Cell - pathology; Carcinoma, Squamous Cell - surgery; Female; Follow-Up Studies; Gastroenterology. Liver. Pancreas. Abdomen; Humans; Male; Medical sciences; Methods; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prognosis; Reoperation; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus; Tumors; Human; Pathology; Squamous cell carcinoma; Anus; Surgery; Digestive diseases; Tumor; Anorectal disease
• ISSN: 0002-9610; 1879-1883
• DOI: 10.1016/S0002-9610(85)80016-7

Epidermoid cancer of the anal margin should be distinguished from that in the canal because of its different clinical and pathologic characteristics, the suitability of local excision for its treatment, and its better overall prognosis. In addition, margin cancer rarely metastasises to visceral sites. Forty-eight patients with epidermoid cancer of the anal margin were reviewed. Two refused treatment, 4 had palliative therapy for advanced, inoperable disease, 31 had local excision, and 11 were treated by abdominoperineal resection. Local excision provided satisfactory results with a corrected 5 year survival of 88 percent, although locoregional recurrence developed in 46 percent of these patients during follow-up. A second local excision or inguinal lymphadenectomy provided good results in the patients with recurrence. Abdominoperineal resection did not provide better overall survival figures.