Successful monochemotherapy of extensive gastrointestinal Kaposi's sarcoma with bowel obstruction in acquired immunodeficiency syndrome

We report the case history of a 28-year-old homosexual man of Caucasian origin whose diagnosis of acquired immunodeficiency syndrome was established one year before admission on the basis of a positive human immunodeficiency virus serology and cutaneous Kaposi's sarcoma. Severe postprandial vom...

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Bibliographic Details
Published inZeitschrift für Gastroenterologie Vol. 32; no. 12; p. 688
Main Authors Lingenfelser, T, Daiss, W, Overkamp, D, Weber, P
Format Journal Article
LanguageEnglish
Published Germany 01.12.1994
Subjects
Adult
Duodenal Obstruction - diagnosis
Duodenal Obstruction - drug therapy
Endoscopy, Gastrointestinal
Gastrointestinal Neoplasms - diagnosis
Gastrointestinal Neoplasms - drug therapy
HIV Infections - complications
HIV Infections - drug therapy
Humans
Male
Sarcoma, Kaposi - diagnosis
Sarcoma, Kaposi - drug therapy
Tomography, X-Ray Computed
Vincristine - administration & dosage
Vincristine - adverse effects
Zidovudine - administration & dosage
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Summary:We report the case history of a 28-year-old homosexual man of Caucasian origin whose diagnosis of acquired immunodeficiency syndrome was established one year before admission on the basis of a positive human immunodeficiency virus serology and cutaneous Kaposi's sarcoma. Severe postprandial vomiting pointed to bowel obstruction in an emaciated, poor risk patient. Endoscopy revealed multifocal, violaceous tumours throughout the upper gastrointestinal tract which, eventually, obstructed the duodenum. Histology confirmed the putative diagnosis of gastrointestinal Kaposi's sarcoma, which responded well to monochemotherapy with vincristine. Significant clinical improvement and repeat endoscopy indicated tumour regression and resolution of bowel obstruction.
ISSN:0044-2771