An implant of a composite of bovine bone morphogenetic protein and plaster of paris for treatment of femoral shaft nonunions

Sixteen patients with nonunion of femoral shaft fractures were treated by implantation of a composite of bovine bone morphogenetic protein and plaster of Paris (bBMP/PLP). There was an average of 1.5 surgical procedures per patient attempting union prior to bBMP/PLP implantation The implant was prep...

Full description

Saved in:
Bibliographic Details
Published inInternational surgery Vol. 81; no. 4; p. 390
Main Authors Bai, M H, Liu, X Y, GE, B F, Yallg, C, Chen, D A
Format Journal Article
LanguageEnglish
Published Italy 01.10.1996
Subjects
Adolescent
Adult
Animals
Bone Morphogenetic Proteins - therapeutic use
Bone Substitutes
Calcium Sulfate - therapeutic use
Cattle
Female
Femoral Fractures - surgery
Fracture Fixation, Internal - methods
Fractures, Ununited - surgery
Humans
Male
Middle Aged
Prostheses and Implants
Online AccessGet more information

Cover

More Information
Summary:Sixteen patients with nonunion of femoral shaft fractures were treated by implantation of a composite of bovine bone morphogenetic protein and plaster of Paris (bBMP/PLP). There was an average of 1.5 surgical procedures per patient attempting union prior to bBMP/PLP implantation The implant was prepared in an aggregate of 50 mg bBMP in 1 gram of plaster of Paris. It was implanted directly to fill the fracture gaps and packed around the fracture lines. Seventeen operations were done on the 16 patients. Union was obtained in 16 of the 17 operations. The average time of union for the 16 successful operations was 5.7 months. There were no significant clinically manifested postoperative complications.
ISSN:0020-8868