Post-poliomyelitic motor neuron disease. Clinical aspects and its relation to typical motor neuron disease

Eighteen cases of post-poliomyelitic motor neuron disease (PPMND) were found in a series of 869 subjects affected by motor neuron disease (MND). The mean age of onset of acute anterior poliomyelitis (AAP) was 43.6 months. The mean age of onset of MND was 45.9 years. No case had a bulbar onset and hy...

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Bibliographic Details
Published inEuropean neurology Vol. 28; no. 4; p. 177
Main Authors Meineri, P, Brignolio, F, Chiò, A, Mittino, D, Tribolo, A, Schiffer, D
Format Journal Article
LanguageEnglish
Published Switzerland 1988
Subjects
Adult
Female
Humans
Male
Middle Aged
Motor Neurons - pathology
Neuromuscular Diseases - etiology
Neuromuscular Diseases - pathology
Poliomyelitis - complications
Poliomyelitis - mortality
Poliomyelitis - physiopathology
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Summary:Eighteen cases of post-poliomyelitic motor neuron disease (PPMND) were found in a series of 869 subjects affected by motor neuron disease (MND). The mean age of onset of acute anterior poliomyelitis (AAP) was 43.6 months. The mean age of onset of MND was 45.9 years. No case had a bulbar onset and hyperreflexia was found in only 2 subjects, one of them having also bilateral extensor plantar response. The survival curve showed a better course of these cases, compared to typical MND (TMND). The present study seems to indicate that PPMND and TMND are different diseases.
ISSN:0014-3022
DOI:10.1159/000116261