Lower limb pain in thalassemia

A group of 67 homozygous beta thalassemic patients was investigated for disturbances related to their lower limbs. Thirty-six patients presented a variety of complaints. Four distinct types of pain were found. Ischemic crampy muscle pain in 12 patients. Postural pulsating pain after activity or prol...

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Bibliographic Details
Published inJournal of rheumatology Vol. 12; no. 3; p. 529
Main Authors Finsterbush, A, Ferber, I, Mogle, P
Format Journal Article
LanguageEnglish
Published Canada 01.06.1985
Subjects
Adolescent
Adult
Bone and Bones - diagnostic imaging
Bone and Bones - physiopathology
Child
Child, Preschool
Female
Fractures, Bone - physiopathology
Homozygote
Humans
Inflammation - physiopathology
Ischemia - physiopathology
Leg
Male
Pain - classification
Pain - physiopathology
Posture
Pressure
Radiography
Thalassemia - diagnostic imaging
Thalassemia - genetics
Thalassemia - physiopathology
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Summary:A group of 67 homozygous beta thalassemic patients was investigated for disturbances related to their lower limbs. Thirty-six patients presented a variety of complaints. Four distinct types of pain were found. Ischemic crampy muscle pain in 12 patients. Postural pulsating pain after activity or prolonged standing was described by 18 patients. High intraosseous pressure was found in a significant number of these patients. Post transfusion hemosiderosis producing synovitis was diagnosed in 2 patients. Four additional patients presented acute self-limiting episodes of pain. This pain was probably due to microfractures. Some patients presented a combination of various pain patterns.
ISSN:0315-162X