Cytologic features of well-differentiated sclerosing liposarcoma in aspirated samples

The histologic, cytologic and ultrastructural features of two cases of a rare variant of liposarcoma, the well-differentiated sclerosing type, are presented. These tumors are characterized by lipoblasts (in different stages of development), atypical fibroblasts, multinucleated floret cells, lipocyte...

Full description

Saved in:
Bibliographic Details
Published inActa cytologica Vol. 32; no. 6; p. 896
Main Authors Shattuck, M C, Victor, T A
Format Journal Article
LanguageEnglish
Published Switzerland 01.11.1988
Subjects
Aged
Cell Nucleus - pathology
Collagen - analysis
Cytoplasm - pathology
Diagnosis, Differential
Female
Fibroblasts - pathology
Humans
Lipid Metabolism
Liposarcoma - pathology
Male
Mediastinal Neoplasms - pathology
Microscopy, Electron
Vacuoles - pathology
Online AccessGet more information

Cover

More Information
Summary:The histologic, cytologic and ultrastructural features of two cases of a rare variant of liposarcoma, the well-differentiated sclerosing type, are presented. These tumors are characterized by lipoblasts (in different stages of development), atypical fibroblasts, multinucleated floret cells, lipocytes and delicate, dispersed collagen. The differential diagnosis includes other types of liposarcoma and three benign lipomatous lesions: the pleomorphic lipoma, the atypical lipoma and the spindle cell lipoma. The latter three neoplasms are composed of fibroblasts, lipocytes and coarse collagen and may have typical lipoblastlike or fibroblastic cells. Given the difficulty in distinguishing these lesions, both cytologically and histologically, the clinical presentation and the tumor location become essential in rendering the diagnosis of sclerosing liposarcoma.
ISSN:0001-5547