Systemic cytomegalovirus infection mimicking an exacerbation of Wegener's granulomatosis

A patient with Wegener's granulomatosis developed a systemic cytomegalovirus infection that mimicked an exacerbation of her vasculitis including pulmonary infiltrates, renal insufficiency, and cutaneous necrotizing ulcers. All of her symptoms resolved with ganciclovir. Physicians should maintai...

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Bibliographic Details
Published inJournal of rheumatology Vol. 20; no. 1; p. 155
Main Authors Weiss, D J, Greenfield, Jr, J W, O'Rourke, K S, McCune, W J
Format Journal Article
LanguageEnglish
Published Canada 01.01.1993
Subjects
Aged
Cyclophosphamide - therapeutic use
Cytomegalovirus Infections - diagnosis
Cytomegalovirus Infections - drug therapy
Diagnosis, Differential
Female
Ganciclovir - therapeutic use
Granulomatosis with Polyangiitis - diagnosis
Granulomatosis with Polyangiitis - drug therapy
Humans
Lung - diagnostic imaging
Lung - pathology
Prednisone - therapeutic use
Radiography, Thoracic
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Summary:A patient with Wegener's granulomatosis developed a systemic cytomegalovirus infection that mimicked an exacerbation of her vasculitis including pulmonary infiltrates, renal insufficiency, and cutaneous necrotizing ulcers. All of her symptoms resolved with ganciclovir. Physicians should maintain a high index of suspicion for similar presentations in other patients with vasculitis with or without immunosuppressive therapy.
ISSN:0315-162X