Inflammatory pseudotumor of the spleen: a rare entity that may mimic hematopoietic malignancy

A case of benign inflammatory pseudotumor of the spleen is described in a 71-year-old man who presented with left upper quadrant pain and anemia. Definitive diagnosis was made by a combination of microscopic examination with immunohistochemical stains and flow cytometry studies. To our knowledge thi...

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Bibliographic Details
Published inThe American surgeon Vol. 61; no. 12; p. 1067
Main Authors McHenry, C R, Perzy-Gall, H B, Mardini, G, Chung-Park, M
Format Journal Article
LanguageEnglish
Published United States 01.12.1995
Subjects
Aged
Diagnosis, Differential
Flow Cytometry
Follow-Up Studies
Granuloma, Plasma Cell - diagnosis
Granuloma, Plasma Cell - surgery
Humans
Immunohistochemistry
Lymphoproliferative Disorders - diagnosis
Male
Organ Size
Splenic Diseases - diagnosis
Splenic Diseases - surgery
Tomography, X-Ray Computed
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Summary:A case of benign inflammatory pseudotumor of the spleen is described in a 71-year-old man who presented with left upper quadrant pain and anemia. Definitive diagnosis was made by a combination of microscopic examination with immunohistochemical stains and flow cytometry studies. To our knowledge this is only the 24th reported case of inflammatory pseudotumor involving the spleen. Recognition of this rare entity is important because the clinical manifestations and radiographic features may be indistinguishable from a malignant lymphoproliferative disorder. The clinical presentation, radiographic findings, gross and microscopic features, results of surgery, and long-term follow up are reviewed for our case and the previously reported cases in the literature.
ISSN:0003-1348