Primary syphilis and nonimmune fetal hydrops in a penicillin-allergic woman. A case report

The incidence of congenital syphilis is on the rise. Penicillin continues to be the drug of choice for it during pregnancy. A penicillin-allergic woman with primary stage syphilis who was treated initially with erythromycin presented with fever and nonimmune fetal hydrops secondary to an intrauterin...

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Bibliographic Details
Published inJournal of reproductive medicine Vol. 39; no. 5; p. 412
Main Authors ElTabbakh, G H, Elejalde, B R, Broekhuizen, F F
Format Journal Article
LanguageEnglish
Published United States 01.05.1994
Subjects
Adult
Desensitization, Immunologic
Drug Hypersensitivity - drug therapy
Drug Hypersensitivity - etiology
Erythromycin - therapeutic use
Female
Humans
Hydrops Fetalis - diagnostic imaging
Hydrops Fetalis - etiology
Infant, Newborn
Infant, Small for Gestational Age
Male
Penicillins - therapeutic use
Pregnancy
Pregnancy Complications, Infectious - drug therapy
Syphilis - drug therapy
Ultrasonography, Prenatal
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Summary:The incidence of congenital syphilis is on the rise. Penicillin continues to be the drug of choice for it during pregnancy. A penicillin-allergic woman with primary stage syphilis who was treated initially with erythromycin presented with fever and nonimmune fetal hydrops secondary to an intrauterine syphilitic infection. Following desensitization and penicillin therapy the fetal hydrops disappeared, the pregnancy continued to term, and the patient delivered a small-for-gestational-age but other-wise normal infant who continued to do well up to 1 year of age.
ISSN:0024-7758