Hydrocortisone, heparin, and peripheral intravenous infusion

We studied the effect of low-dose hydrocortisone and heparin added to peripheral intravenous fluid on episodes and severity of thrombophlebitis. Osmolal solutions of 860 mOsm/kg H2O with heparin and hydrocortisone (feed A) and without heparin and hydrocortisone (feed B) were infused into surgical an...

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Bibliographic Details
Published inNutrition (Burbank, Los Angeles County, Calif.) Vol. 10; no. 3; p. 211
Main Authors Roongpisuthipong, C, Puchaiwatananon, O, Songchitsomboon, S, Kanjanapanjapol, S
Format Journal Article
LanguageEnglish
Published United States 01.05.1994
Subjects
Adult
Aged
Female
Heparin - administration & dosage
Heparin - therapeutic use
Humans
Hydrocortisone - administration & dosage
Hydrocortisone - therapeutic use
Infusions, Intravenous
Male
Middle Aged
Osmolar Concentration
Parenteral Nutrition - adverse effects
Thrombophlebitis - etiology
Thrombophlebitis - prevention & control
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Summary:We studied the effect of low-dose hydrocortisone and heparin added to peripheral intravenous fluid on episodes and severity of thrombophlebitis. Osmolal solutions of 860 mOsm/kg H2O with heparin and hydrocortisone (feed A) and without heparin and hydrocortisone (feed B) were infused into surgical and ear, nose, and throat patients for peripheral intravenous nutrition. The addition of heparin (500 U/L) and hydrocortisone (10 mg/L) in 10% dextrose in half-strength normal saline and 500 ml 5% crystalline amino acid solution infused simultaneously via a Y line significantly reduced the episodes and severity of thrombophlebitis. Thus, the administration of low-dose hydrocortisone and heparin with peripheral fluids is beneficial in preventing thrombophlebitis.
ISSN:0899-9007
1873-1244