Elastase-1-secreting acinar cell carcinoma of the pancreas. A cytologic, electron microscopic and histochemical study

A case of acinar cell carcinoma of the pancreas was diagnosed by fine needle aspiration cytology during surgery. The cytologic characteristics of this neoplasm are described. Electron microscopy disclosed numerous zymogen granules in the tumor while histochemistry demonstrated the presence of elasta...

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Bibliographic Details
Published inActa cytologica Vol. 33; no. 2; p. 157
Main Authors Ishihara, A, Sanda, T, Takanari, H, Yatani, R, Liu, P I
Format Journal Article
LanguageEnglish
Published Switzerland 01.03.1989
Subjects
Aged
Amylases - metabolism
Biopsy, Needle
Carcinoma - pathology
Carcinoma - secretion
Female
Humans
Immunohistochemistry
Microscopy, Electron
Pancreatic Elastase - secretion
Pancreatic Neoplasms - pathology
Pancreatic Neoplasms - secretion
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Summary:A case of acinar cell carcinoma of the pancreas was diagnosed by fine needle aspiration cytology during surgery. The cytologic characteristics of this neoplasm are described. Electron microscopy disclosed numerous zymogen granules in the tumor while histochemistry demonstrated the presence of elastase-1. Serum elastase-1 levels were markedly elevated. The cytologic differential diagnosis of pancreatic tumors is discussed.
ISSN:0001-5547