Effect of diazinon on freeze-fracture images of microvilli of intestinal epithelial cells of Tilapia nilotica

The effect of the organophosphate insecticide, diazinon on the intramembranous particles (IMPs) of the microvilli of the intestinal epithelial cells of Tilapia nilotica fish was studied using freeze-fracture technique. Exposing fish to different repeated concentrations of diazinon (1/2LC50) caused a...

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Bibliographic Details
Published inZeitschrift für Ernährungswissenschaft Vol. 30; no. 4; p. 268
Main Authors Sakr, S A, Gabr, S A, el-Saadany, M M
Format Journal Article
LanguageEnglish
Published Germany 01.12.1991
Subjects
Animals
Diazinon - toxicity
Epithelium - drug effects
Epithelium - ultrastructure
Fishes - anatomy & histology
Freeze Fracturing
Fresh Water
Intestines - drug effects
Intestines - ultrastructure
Microscopy, Electron
Microvilli - drug effects
Microvilli - ultrastructure
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Summary:The effect of the organophosphate insecticide, diazinon on the intramembranous particles (IMPs) of the microvilli of the intestinal epithelial cells of Tilapia nilotica fish was studied using freeze-fracture technique. Exposing fish to different repeated concentrations of diazinon (1/2LC50) caused a significant decrease in population density of IMPs in P- and E-faces. IMPs of microvilli found in intestinal epithelial cells are thought to represent many kinds of proteins including enzymes. In the present work, it is suggested that diazinon induced a reduction in enzymatic content of the membrane which was accompanied by a decrease in IMPs density of the microvilli.
ISSN:0044-264X
DOI:10.1007/BF01651956