Desmoplastic fibroma of the temporal bone

Desmoplastic fibroma is a benign, locally aggressive, intraosseous neoplasm with a propensity for local recurrence. Desmoplastic fibroma most commonly originates within the mandible (70% of cases), and long bones with rare lesions reported in the maxillary, frontal, and parietal bones. We report two...

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Bibliographic Details
Published inThe American journal of otology (New York, N.Y.) Vol. 18; no. 5; p. 627
Main Authors Pensak, M L, Nestok, B R, Van Loveren, H, Shumrick, K A
Format Journal Article
LanguageEnglish
Published United States 01.09.1997
Subjects
Adult
Female
Fibroma, Desmoplastic - diagnostic imaging
Fibroma, Desmoplastic - pathology
Humans
Skull Neoplasms - diagnostic imaging
Skull Neoplasms - pathology
Temporal Bone - diagnostic imaging
Temporal Bone - pathology
Tomography, X-Ray Computed
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Summary:Desmoplastic fibroma is a benign, locally aggressive, intraosseous neoplasm with a propensity for local recurrence. Desmoplastic fibroma most commonly originates within the mandible (70% of cases), and long bones with rare lesions reported in the maxillary, frontal, and parietal bones. We report two patients with desmoplastic fibroma arising within the temporal bone. Case report and literature review. Two patients with desmoplastic fibroma with intracranial and extra cranial growth patterns are presented. Both were young females with aural fullness and decreased hearing. Diagnostic and therapeutic. Both tumors were surgically extirpated and the patients have remained disease free for 18-48 months. Neither tumor expressed estrogen or progesterone receptors. Desmoplastic fibroma is a highly invasive local destructive lesion which is best treated by nondestructive surgical intervention. Immunohistochemical analysis may demonstrate hormonal receptors, in which case Tamoxifen may reduce recurrence.
ISSN:0192-9763