The role of mast cells in bronchial asthma: mechanisms and possible therapeutic implications

The role of mast cells in human biology is important and complex. They probably play a dual role both in protecting the host and in causing disease symptoms. For example: mast-cell-mediated vasopermeability is an important manifestation of asthma, but it also provides access of antibody and other bl...

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Bibliographic Details
Published inThe Mount Sinai journal of medicine Vol. 58; no. 6; p. 472
Main Author Marom, Z M
Format Journal Article
LanguageEnglish
Published United States 01.11.1991
Subjects
Animals
Asthma - drug therapy
Asthma - pathology
Asthma - physiopathology
Bronchial Spasm - physiopathology
Humans
Mast Cells - physiology
Mast Cells - secretion
Mucous Membrane - pathology
Mucus - secretion
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Summary:The role of mast cells in human biology is important and complex. They probably play a dual role both in protecting the host and in causing disease symptoms. For example: mast-cell-mediated vasopermeability is an important manifestation of asthma, but it also provides access of antibody and other blood factors which are brought to the tissue and help in defense. Therefore, these cells, with their abundant mediators, may play an important role in both homeostasis and disease.
ISSN:0027-2507