Lithium and rubidium activities on platelet aggregation

Lithium (Li) has been shown to increase the platelet number after chemotherapy. The present paper suggests that Li may increase the platelet aggregation induced by sub-optimal concentrations of ADP. Conversely, rubidium does not modify platelet aggregation in the present experiments.

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Bibliographic Details
Published inDrugs under experimental and clinical research Vol. 17; no. 6; p. 313
Main Authors La Gioia, A, Petrini, M, Carulli, G, Lofaro, A
Format Journal Article
LanguageEnglish
Published Switzerland 1991
Subjects
Adenosine Diphosphate - pharmacology
Humans
Kinetics
Lithium - pharmacology
Platelet Aggregation - drug effects
Rubidium - pharmacology
Time Factors
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Summary:Lithium (Li) has been shown to increase the platelet number after chemotherapy. The present paper suggests that Li may increase the platelet aggregation induced by sub-optimal concentrations of ADP. Conversely, rubidium does not modify platelet aggregation in the present experiments.
ISSN:0378-6501