Concentrations of purine nucleotides and purine and pyrimidine bases in cerebrospinal fluid of neurologically healthy children

The concentrations of the nucleotides AMP and IMP, the nucleosides adenosine, guanosine and inosine, the purine bases adenine, guanine, hypoxanthine and xanthine, urate, and the pyrimidine bases cytosine, thymine and uracil were determined by high performance liquid chromatography in the cerebrospin...

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Bibliographic Details
Published inEuropean journal of clinical chemistry and clinical biochemistry Vol. 30; no. 11; p. 761
Main Authors Castro-Gago, M, Camiña, F, Lojo, S, Rodríguez-Segade, S, Rodríguez-Núñez, A
Format Journal Article
LanguageEnglish
Published Germany 01.11.1992
Subjects
Adolescent
Child
Child, Preschool
Chromatography, High Pressure Liquid
Humans
Infant
Purine Nucleotides - cerebrospinal fluid
Purines - cerebrospinal fluid
Pyrimidines - cerebrospinal fluid
Reference Values
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Summary:The concentrations of the nucleotides AMP and IMP, the nucleosides adenosine, guanosine and inosine, the purine bases adenine, guanine, hypoxanthine and xanthine, urate, and the pyrimidine bases cytosine, thymine and uracil were determined by high performance liquid chromatography in the cerebrospinal fluid of 63 children aged between 1 month and 13 years who showed no sign of neurological disease. The results are compared with those of other authors, and used to establish reference ranges for the above metabolites in the cerebrospinal fluid of children.
ISSN:0939-4974