Disseminated infection of Pneumocystis carinii in a patient with the acquired immunodeficiency syndrome

• Published in: Virchows Archiv. A, Pathological anatomy and histopathology Vol. 414; no. 6; p. 523
• Main Authors: Matsuda, S, Urata, Y, Shiota, T, Yamada, M, Yoshikawa, H, Tegoshi, T, Okada, M, Nakamura, H, Kitaoka, T, Ashihara, T
• Format: Journal Article
• Language: English
• Published: Germany 1989
• Subjects: Acquired Immunodeficiency Syndrome - complications; Acquired Immunodeficiency Syndrome - pathology; Adult; Animals; Humans; Intestine, Small - microbiology; Intestine, Small - pathology; Lymph Nodes - microbiology; Lymph Nodes - pathology; Male; Opportunistic Infections - complications; Opportunistic Infections - pathology; Pneumocystis - isolation & purification; Pneumonia, Pneumocystis - complications; Pneumonia, Pneumocystis - pathology
• ISSN: 0174-7398
• DOI: 10.1007/BF00781710

This report describes the histopathology of a disseminated Pneumocystis carinii infection in a 24-year-old Japanese male haemophiliac diagnosed as having the acquired immunodeficiency syndrome. He developed respiratory symptoms, and Pneumocystis carinii pneumonia was confirmed by transbronchial lung biopsy. On the 70th day of hospitalization the patient died. Autopsy findings revealed Pneumocystis carinii not only in the lungs but also in the stomach, jejunum, ileum, colon, mesoappendix, abdominal lymph nodes, diaphragm, and thyroid gland.