Can we assess the changes of ventricular filling resulting from acute allograft rejection with Doppler echocardiography?

We investigated the value of several Doppler echocardiographic measurements for the diagnosis of acute allograft rejection after orthotopic heart transplantation. In all, 144 transmitral flow velocity curves and 159 internal jugular venous flow velocity curves were recorded by continuous wave Dopple...

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Bibliographic Details
Published inThe Journal of heart transplantation Vol. 7; no. 6; p. 430
Main Authors Forster, T, McGhie, J, Rijsterborgh, H, van de Borden, S, Laird-Meeter, K, Balk, A, Essed, C, Roelandt, J
Format Journal Article
LanguageEnglish
Published United States 01.11.1988
Subjects
Adult
Biopsy
Blood Flow Velocity
Coronary Circulation
Echocardiography, Doppler
Graft Rejection
Heart Transplantation
Humans
Myocardium - pathology
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Summary:We investigated the value of several Doppler echocardiographic measurements for the diagnosis of acute allograft rejection after orthotopic heart transplantation. In all, 144 transmitral flow velocity curves and 159 internal jugular venous flow velocity curves were recorded by continuous wave Doppler echocardiography, and the results were compared with the histologic findings. The recordings were evaluated with a computer-aided analysis system. The Doppler measurements did not show any significant correlation with the biopsy results. Only one recording obtained during a moderate acute rejection episode supported the hypothesis about the relation between jugular venous flow and cardiac rejection. We conclude that these Doppler echocardiographic measurements are not suitable to detect acute allograft rejection noninvasively.
ISSN:0887-2570