Pancreatic giant cell carcinoma of the osteoclastic type: response to 5-fluorouracil and radiation

A case of pancreatic giant cell carcinoma of the osteoclastic type is presented. The findings of endoscopic retrograde cholangiography, angiography, computerized tomography, and magnetic resonance imaging scans are described for the first time for this rare neoplasm, showing a large, nonresectable p...

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Bibliographic Details
Published inThe American journal of gastroenterology Vol. 81; no. 11; p. 1093
Main Authors Drexler, L J, Mitre, R J, Madan, E, Zidar, B L
Format Journal Article
LanguageEnglish
Published United States 01.11.1986
Subjects
Aged
Carcinoma - drug therapy
Carcinoma - pathology
Carcinoma - radiotherapy
Combined Modality Therapy
Fluorouracil - therapeutic use
Humans
Male
Pancreatic Neoplasms - drug therapy
Pancreatic Neoplasms - pathology
Pancreatic Neoplasms - radiotherapy
Pancreatic Neoplasms - therapy
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Summary:A case of pancreatic giant cell carcinoma of the osteoclastic type is presented. The findings of endoscopic retrograde cholangiography, angiography, computerized tomography, and magnetic resonance imaging scans are described for the first time for this rare neoplasm, showing a large, nonresectable pancreatic tumor. The patient's clinical course is followed during treatment with 5-fluorouracil and radiation therapy, documenting response by computerized tomography scan. The cases reported in the literature are reviewed and surgical and medical treatments are discussed. A combination of 5-fluorouracil and radiation therapy is the first medical treatment with a documented response.
ISSN:0002-9270
DOI:10.1111/j.1572-0241.1986.tb01401.x