A model for involutional bone loss

Bone mass of the total skeleton and distal radius were measured by in vivo neutron activation analysis and single photon absorptiometry, respectively, in 403 healthy white women and 151 healthy white men. In addition, the density of L-2 to L-4 (bone mineral content of the spine [BMCs]) was measured...

Full description

Saved in:
Bibliographic Details
Published inThe Journal of laboratory and clinical medicine Vol. 106; no. 6; p. 630
Main Authors Aloia, J F, Vaswani, A, Ellis, K, Yuen, K, Cohn, S H
Format Journal Article
LanguageEnglish
Published United States 01.12.1985
Subjects
Adult
Aged
Aging
Bone and Bones - analysis
Bone and Bones - diagnostic imaging
Bone Resorption - diagnostic imaging
Bone Resorption - metabolism
Calcium - analysis
Female
Fractures, Spontaneous - diagnostic imaging
Fractures, Spontaneous - metabolism
Humans
Lumbar Vertebrae - analysis
Lumbar Vertebrae - diagnostic imaging
Male
Menopause
Middle Aged
Minerals - analysis
Models, Biological
Neutron Activation Analysis
Organ Size
Osteoporosis - diagnostic imaging
Osteoporosis - metabolism
Radionuclide Imaging
Radius - analysis
Radius - diagnostic imaging
Regression Analysis
Sex Characteristics
Online AccessGet more information

Cover

More Information
Summary:Bone mass of the total skeleton and distal radius were measured by in vivo neutron activation analysis and single photon absorptiometry, respectively, in 403 healthy white women and 151 healthy white men. In addition, the density of L-2 to L-4 (bone mineral content of the spine [BMCs]) was measured by dual photon absorptiometry in 159 of these women and in 56 women with the vertebral crush fracture syndrome. The rate of loss of total body calcium (TBCa) and bone mineral content of the radius (BMCr) was linear in men and was slower than in women. The best fit for TBCa and the bone mineral content of the distal radius and spine as a function of age in women was with a two-phase regression. The TBCa and BMCr could be used as well as BMCs to identify women with crush fractures. The ratios of BMCs/TBCa, BMCs/BMCr, and TBCa/BMCr did not differ among women with crush fractures and age-matched normal individuals. Our data do not support the hypothesis that women with vertebral crush fractures have preferential loss of spinal bone.
ISSN:0022-2143