A prospective study of chloramphenicol induced aplastic anaemia in Nigerians

A five-year prospective study of chloramphenicol induced aplastic anaemia in Nigerians was undertaken. Five proven cases were seen, representing 45.5% of all cases of aplastic anaemia diagnosed during the period of study and 1.0 cases per year. Chloramphenicol induced aplastic anaemia is rare (only...

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Bibliographic Details
Published inTropical and geographical medicine Vol. 45; no. 4; p. 159
Main Authors Durosinmi, M A, Ajayi, A A
Format Journal Article
LanguageEnglish
Published Netherlands 1993
Subjects
Adolescent
Adult
Anemia, Aplastic - chemically induced
Anemia, Aplastic - epidemiology
Anemia, Aplastic - prevention & control
Chloramphenicol - adverse effects
Female
Humans
Incidence
Middle Aged
Nigeria - epidemiology
Prognosis
Prospective Studies
Self Medication
Nigeria
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Summary:A five-year prospective study of chloramphenicol induced aplastic anaemia in Nigerians was undertaken. Five proven cases were seen, representing 45.5% of all cases of aplastic anaemia diagnosed during the period of study and 1.0 cases per year. Chloramphenicol induced aplastic anaemia is rare (only 0.002% of all new non-obstetric patients seen in the hospital during the period of study) but preventable. Restriction of the drug or its total withdrawal is recommended.
ISSN:0041-3232