An open, parallel groups, study of the importance of thoroughness of application in the treatment of psoriasis with a dithranol cream (Micanol)

Earlier studies have suggested that the rate of healing is somewhat slower for the new microencapsulated dithranol formulation, Micanol, than for petrolatum or paraffin based formulations. The less smeary Micanol formulation may need more vigorous application. A population of 29 patients with chroni...

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Bibliographic Details
Published inActa dermato-venereologica. Supplementum Vol. 172; p. 23
Main Authors Mørk, N J, Austad, J, Brolund, L
Format Journal Article
LanguageEnglish
Published Norway 1992
Subjects
Administration, Topical
Adult
Aged
Anthralin - administration & dosage
Anthralin - adverse effects
Anthralin - therapeutic use
Female
Humans
Male
Middle Aged
Ointments
Psoriasis - drug therapy
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Summary:Earlier studies have suggested that the rate of healing is somewhat slower for the new microencapsulated dithranol formulation, Micanol, than for petrolatum or paraffin based formulations. The less smeary Micanol formulation may need more vigorous application. A population of 29 patients with chronic, stable plaque-type psoriasis was divided into two groups, both receiving short contact treatment. One group received standard patient information while the other received information stressing the importance of being thorough when rubbing the dithranol cream into the lesions. Regarding composite sign severity score, there was a significant difference (about 50%) in favour of the extra information group after 6 weeks. This result suggests that thoroughness of application is an important factor for the rate of healing in short contact treatment of psoriasis with Micanol.
ISSN:0365-8341