Chronic mucocutaneous candidiasis

Chronic mucocutaneous candidiasis should be viewed as a spectrum of disorders in which the patients have persistent and/or recurrent candidiasis of the skin, nails and mucous membranes. Some of the conditions have genetic predispositions. A common immunologic abnormality is failure of the patient�...

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Bibliographic Details
Published inThe Pediatric infectious disease journal Vol. 20; no. 2; p. 197
Main Author Kirkpatrick, C H
Format Journal Article
LanguageEnglish
Published United States 01.02.2001
Subjects
Antifungal Agents - therapeutic use
Candidiasis, Chronic Mucocutaneous - complications
Candidiasis, Chronic Mucocutaneous - diagnosis
Candidiasis, Chronic Mucocutaneous - immunology
Candidiasis, Chronic Mucocutaneous - therapy
Humans
Immunity, Cellular
Immunocompetence
Immunologic Deficiency Syndromes - complications
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Summary:Chronic mucocutaneous candidiasis should be viewed as a spectrum of disorders in which the patients have persistent and/or recurrent candidiasis of the skin, nails and mucous membranes. Some of the conditions have genetic predispositions. A common immunologic abnormality is failure of the patient's T lymphocytes to produce cytokines that are essential for expression of cell-mediated immunity to Candida. Antifungal drugs are effective in clearing the infections, and treatments that restore cellular immunity have produced long term remissions.
ISSN:0891-3668
DOI:10.1097/00006454-200102000-00017