Needle aspiration cytology of a benign and a malignant schwannoma

The histologic and cytologic features of an uncommon solitary, malignant schwannoma and a benign schwannoma are presented. The benign tumor revealed characteristic interlacing fascicles of spindle-shaped cells on both histology and cytology. The malignant schwannoma produced a variable histologic pa...

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Bibliographic Details
Published inActa cytologica Vol. 28; no. 2; p. 157
Main Authors Hood, I C, Qizilbash, A H, Young, J E, Archibald, S D
Format Journal Article
LanguageEnglish
Published Switzerland 01.03.1984
Subjects
Aged
Biopsy, Needle
Cell Nucleus - pathology
Cytoplasm - pathology
Female
Humans
Male
Middle Aged
Nervous System Neoplasms - analysis
Nervous System Neoplasms - pathology
Neurilemmoma - analysis
Neurilemmoma - pathology
S100 Proteins - analysis
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Summary:The histologic and cytologic features of an uncommon solitary, malignant schwannoma and a benign schwannoma are presented. The benign tumor revealed characteristic interlacing fascicles of spindle-shaped cells on both histology and cytology. The malignant schwannoma produced a variable histologic pattern that was selectively sampled from a recurrence in a scar; only obviously malignant, undifferentiated, spindle-shaped cells not capable of further characterization were seen on cytology. Preliminary experience with immunoperoxidase staining for the neural crest marker S-100 protein has been encouraging and may permit identification of these tumors on aspiration smears.
ISSN:0001-5547
1938-2650