Cyclic Hematopoiesis: animal models

The four existing animal models of cyclic hematopoiesis are briefly described. The unusual erythropoietin (Ep) responses of the W/Wv mouse, the Sl/Sld mouse, and cyclic hematopoietic dog are reviewed. The facts reviewed indicate that the bone marrow itself is capable of influencing regulatory events...

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Bibliographic Details
Published inExperimental hematology Vol. 11; no. 7; p. 571
Main Authors Jones, J B, Lange, R D
Format Journal Article
LanguageEnglish
Published Netherlands 01.08.1983
Subjects
Anemia - blood
Anemia - chemically induced
Animals
Bone Marrow - ultrastructure
Bone Marrow Cells
Disease Models, Animal
Dog Diseases - genetics
Dogs
Erythropoiesis - drug effects
Erythropoietin - biosynthesis
Hematopoiesis - drug effects
Humans
Hypoxia - blood
Lithium - therapeutic use
Mice
Mice, Inbred Strains
Mink
Neutropenia - blood
Neutropenia - chemically induced
Neutropenia - genetics
Periodicity
Prednisolone - therapeutic use
Strontium Radioisotopes - administration & dosage
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Summary:The four existing animal models of cyclic hematopoiesis are briefly described. The unusual erythropoietin (Ep) responses of the W/Wv mouse, the Sl/Sld mouse, and cyclic hematopoietic dog are reviewed. The facts reviewed indicate that the bone marrow itself is capable of influencing regulatory events of hematopoiesis.
ISSN:0301-472X