LPO and antioxidant defense in the stomach of albino rats injected with angiotensin II and enalapril maleate

The effects of components of angiotensin II system on LPO and antioxidant defense in the stomach of adult albino rats were studied using biochemical and chemiluminescent methods. Five intraperitoneal injections of angiotensin II in a dose of 100 micro/kg activated LPO and inhibited antioxidant proce...

Full description

Saved in:
Bibliographic Details
Published inBulletin of experimental biology and medicine Vol. 135; no. 4; pp. 343 - 345
Main Authors Pikalova, V M, Postupaev, V V, Timoshin, S S
Format Journal Article
LanguageEnglish
Published United States Springer Nature B.V 01.04.2003
Subjects
Angiotensin II - pharmacology
Angiotensin-Converting Enzyme Inhibitors - administration & dosage
Angiotensin-Converting Enzyme Inhibitors - pharmacology
Animals
Antioxidants - metabolism
Enalapril - administration & dosage
Enalapril - pharmacology
Gastric Mucosa - metabolism
Humans
Lipid Peroxides - metabolism
Male
Rats
Stomach - drug effects
Vasoconstrictor Agents - pharmacology
Online AccessGet full text

Cover

More Information
Summary:The effects of components of angiotensin II system on LPO and antioxidant defense in the stomach of adult albino rats were studied using biochemical and chemiluminescent methods. Five intraperitoneal injections of angiotensin II in a dose of 100 micro/kg activated LPO and inhibited antioxidant processes in the studied tissues. Oral therapy with enalapril maleate (inhibitor of angiotensin-converting enzyme) in a daily dose of 10 mg/kg for 2 weeks normalized stress-activated LPO processes in gastric tissue.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0007-4888
1573-8221
DOI:10.1023/A:1024652512724