Validation and uses of a Y-chromosome STR 10-plex for forensic and paternity laboratories

• Published in: Journal of forensic sciences Vol. 48; no. 6; p. 1260
• Main Authors: Johnson, Cassie L, Warren, Joseph H, Giles, Robert C, Staub, Rick W
• Format: Journal Article
• Language: English
• Published: United States 01.11.2003
• Subjects: Chromosomes, Human, Y; Continental Population Groups - genetics; DNA Fingerprinting - methods; Electrophoresis, Capillary; Female; Gene Frequency; Genetic Variation; Haplotypes; Humans; Male; Paternity; Polymerase Chain Reaction; Sensitivity and Specificity; Tandem Repeat Sequences

Y-chromosome short tandem repeats (Y-STRs) provide valuable information in cases of rape and questioned paternity, and they allow for the genetic identification of male lineages. The present study validated a Y-STR 10-plex on the ABI PRISM 3100 Genetic Analyzer for use in forensic and paternity labo...