Cerebrospinal fluid pleocytosis in acute lymphoblastic leukemia without central nervous system relapse: a report of three cases

Three patients with acute lymphoblastic leukemia (ALL) developed mononuclear cells in the cerebrospinal fluid (CSF) after a flu-like history during maintenance treatment. None of the patients showed evidence of central nervous system (CNS) involvement by either clinical or laboratory follow-up. Alth...

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Bibliographic Details
Published inTurkish journal of pediatrics Vol. 41; no. 2; pp. 249 - 251
Main Authors Oner, A F, Yetgin, S, Uçkan, D
Format Journal Article
LanguageEnglish
Published Turkey Türk Pediatri Derneği 01.04.1999
Subjects
Bağışıklık sistemi hastalıkları
Beyin omurilik sıvısı
Blood Cells
Central Nervous System Diseases - etiology
Cerebrospinal Fluid
Cerebrospinal Fluid - immunology
Child
Diagnosis, Differential
Hemic and lymphatic diseases
Hemik ve lenfatik hastalıklar
Humans
Immunologic diseases
Involvement
Kan hücreleri
Leukemia, Lymphocytic, Acute
Leukocytes, Mononuclear
Leukocytosis
Leukocytosis - etiology
Lökositoz
Lösemi, lenfositik, akut
Male
Neoplasms
Neoplazmlar
Nüks
Paleositoz
Pleocytosis
Precursor Cell Lymphoblastic Leukemia-Lymphoma - cerebrospinal fluid
Precursor Cell Lymphoblastic Leukemia-Lymphoma - complications
Relapse
Tutulum
Çocuk
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Summary:Three patients with acute lymphoblastic leukemia (ALL) developed mononuclear cells in the cerebrospinal fluid (CSF) after a flu-like history during maintenance treatment. None of the patients showed evidence of central nervous system (CNS) involvement by either clinical or laboratory follow-up. Although the presence of > 5 mononuclear cells/microl in the CSF is important, it may not necessarily indicate CNS disease. Clinical findings, history and cell morphology must be evaluated before deciding on further treatment.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
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ISSN:0041-4301