Living donor liver transplantation in the USA

Living donor liver transplant (LDLT) accounts for a small volume of the transplants in the USA. Due to the current liver allocation system based on the model for end-stage liver disease (MELD), LDLT has a unique role in providing life-saving transplantation for patients with low MELD scores and sign...

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Bibliographic Details
Published inHepatobiliary surgery and nutrition Vol. 5; no. 2; pp. 133 - 140
Main Authors Kim, Peter T W, Testa, Giuliano
Format Journal Article
LanguageEnglish
Published China (Republic : 1949- ) AME Publishing Company 01.04.2016
Subjects
Review
mortality
living donor
Donor risk
left-lobe graft
liver transplantation
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Summary:Living donor liver transplant (LDLT) accounts for a small volume of the transplants in the USA. Due to the current liver allocation system based on the model for end-stage liver disease (MELD), LDLT has a unique role in providing life-saving transplantation for patients with low MELD scores and significant complications from portal hypertension, as well as select patients with hepatocellular carcinoma (HCC). Donor safety is paramount and has been a topic of much discussion in the transplant community as well as the general media. The donor risk appears to be low overall, with a favorable long-term quality of life. The latest trend has been a gradual shift from right-lobe grafts to left-lobe grafts to reduce donor risk, provided that the left lobe can provide adequate liver volume for the recipient.
Bibliography:Contributions: (I) Conception and design: All authors; (II) Administrative support: All authors; (III) Provision of study materials or patients: All authors; (IV) Collection and assembly of data: All authors; (V) Data analysis and interpretation: All authors; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors.
ISSN:2304-3881
2304-389X
DOI:10.3978/j.issn.2304-3881.2015.06.01