New calcium‐free Na2O–Al2O3–P2O5 bioactive glasses with potential applications in bone tissue engineering

Sodium aluminophosphate glasses were evaluated for their bone repair ability. The glasses belonging to the system 45Na2O–xAl2O3‐(55‐x)P2O5, with x = (3, 5, 7, 10 mol%) were prepared by a melt‐quenching method. We assessed the effect of Al2O3 content on the properties of Na2O–Al2O3–P2O5 (NAP) glasses...

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Published inJournal of the American Ceramic Society Vol. 101; no. 2; pp. 602 - 611
Main Authors Jeznach, Oliwia, Gajc, Marcin, Korzeb, Karolina, Kłos, Andrzej, Orliński, Krzysztof, Stępień, Ryszard, Krok‐Borkowicz, Małgorzata, Rumian, Łucja, Pietryga, Krzysztof, Reczyńska, Katarzyna, Pamuła, Elżbieta, Pawlak, Dorota A.
Format Journal Article
LanguageEnglish
Published Columbus Wiley Subscription Services, Inc 01.02.2018
Subjects
alumina
Aluminum oxide
bioactive glass
Biocompatibility
Biological activity
Biomedical materials
Body fluids
bone tissue engineering
Bones
Calcium
calcium‐free bioactive glass
In vitro methods and tests
phosphate glass
Phosphorus pentoxide
Quenching
sodium aluminophosphate glass
Surgical implants
Tissue engineering
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Summary:Sodium aluminophosphate glasses were evaluated for their bone repair ability. The glasses belonging to the system 45Na2O–xAl2O3‐(55‐x)P2O5, with x = (3, 5, 7, 10 mol%) were prepared by a melt‐quenching method. We assessed the effect of Al2O3 content on the properties of Na2O–Al2O3–P2O5 (NAP) glasses, which were characterized by density measurements, DSC analyses, solubility, bioactivity in simulated body fluid and cytocompatibility with MG‐63 cells. To the best of our knowledge, this is the first investigation of calcium‐free Na2O–Al2O3–P2O5 system glasses as bioactive materials for bone tissue engineering.
ISSN:0002-7820
1551-2916
DOI:10.1111/jace.15216