Deep Photoacoustic/Luminescence/Magnetic Resonance Multimodal Imaging in Living Subjects Using High‐Efficiency Upconversion Nanocomposites

• Published in: Advanced materials (Weinheim) Vol. 28; no. 30; pp. 6411 - 6419
• Main Authors: Liu, Yu, Kang, Ning, Lv, Jing, Zhou, Zijian, Zhao, Qingliang, Ma, Lingceng, Chen, Zhong, Ren, Lei, Nie, Liming
• Format: Journal Article
• Language: English
• Published: Germany 01.08.2016
• Subjects: deep imaging; high‐efficiency upconversion luminescence; Imaging; Luminescence; Magnetic resonance; magnetic resonance imaging; multi‐shell structure; Nanocomposites; Nanostructure; photoacoustic (PA) imaging; Tumors; Upconversion; Visualization; deep imaging; multi-shell structure; high-efficiency upconversion luminescence; magnetic resonance imaging; photoacoustic (PA) imaging
• ISSN: 0935-9648; 1521-4095; 1521-4095
• DOI: 10.1002/adma.201506460

A gadolinium‐doped multi‐shell upconversion nanoparticle under 800 nm excitation is synthesized with a 10‐fold fluorescence‐intensity enhancement over that under 980 nm. The nanoformulations exhibit excellent photoacoustic/luminescence/magnetic resonance tri‐modal imaging capabilities, enabling visu...