Rapid determination of fluconazole susceptibilities for clinical specimens with possible polymicrobial Candida spp

The clinical failure to fluconazole therapies had been observed despite susceptible results obtained for the isolate which raised questions about the laboratory methods,3 emergence of resistance after subtherapeutic dosing,4,5 and the possibility of polymicrobial Candida spp infections. The rapidity...

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Bibliographic Details
Published inNew Zealand medical journal Vol. 120; no. 1255; p. U2567
Main Authors Chiew, Yoke-Fong, Inwood, Holly
Format Journal Article
LanguageEnglish
Published New Zealand Pasifika Medical Association Group (PMAG) 01.06.2007
Subjects
Antifungal Agents - pharmacology
Antifungal Agents - therapeutic use
Blood - microbiology
Candida - drug effects
Candida - isolation & purification
Candidiasis - drug therapy
Candidiasis - microbiology
Drug dosages
Epidemiology
Fluconazole - pharmacology
Fluconazole - therapeutic use
Health care
Humans
Infections
Laboratories
Microbial Sensitivity Tests - methods
Older people
Urine - microbiology
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Summary:The clinical failure to fluconazole therapies had been observed despite susceptible results obtained for the isolate which raised questions about the laboratory methods,3 emergence of resistance after subtherapeutic dosing,4,5 and the possibility of polymicrobial Candida spp infections. The rapidity with which candidal infections are evolving include emergence of fluconazole resistance in Candida albicans as well as the changing epidemiology to increasing prevalence of known fluconazole-resistant Candida spp.11,12 A rapid screen for their detection in the clinical laboratory is therefore warranted.
Bibliography:SourceType-Other Sources-1
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ObjectType-Correspondence-1
ISSN:1175-8716