Effect of fluorine ion addition on structural, thermal, mechanical, solubility and biocompatibility characteristics of hydroxyapatite nanopowders

• Published in: Advances in applied ceramics Vol. 109; no. 4; pp. 200 - 212
• Main Authors: Eslami, H, Solati-Hashjin, M, Tahriri, M
• Format: Journal Article
• Language: English
• Published: 01.04.2010
• Subjects: Discs; Disks; Fluorine; Hydroxyapatite; Nanocomposites; Nanomaterials; Nanostructure; Sintering (powder metallurgy)
• ISSN: 1743-6753; 1743-6761
• DOI: 10.1179/174367509X12503626841550

In this study, the effect of fluorine ion addition on the structural, thermal, mechanical and solubility characteristics of hydroxyapatite nanopowders was investigated. The fluorine substituted hydroxyapatite powders with compositions of Ca sub(5)(PO sub(4)) sub(3)(OH) sub(1-x)F sub(x) [x = 0 (hydroxyapatite), x = 0.68 (fluorhydroxyapatite) and x = 0.97 (fluorapatite)] were prepared. The powders were uniaxially pressed and were formed as disc shape. Subsequently, sinterability and thermal stability of disc samples were compared together. Also the effects simultaneously of fluoride content and temperature on the lattice parameters, crystallites size, microstrain and microstructure of the samples were examined. The sintering density and flexural strength of these samples were evaluated with the sintering temperature. Finally, the in vitro dissolution studies of the apatite samples were performed at osteoclastic resorption conditions. The above mentioned experimental results showed that the fluorine content had significant impact on the sintering behaviour, densification and mechanical properties of the hydroxyapatite nanopowders.